|RPG published by
Your mind is software. Program it.
Your body is a shell. Change it.
Death is a disease. Cure it.
Extinction is approaching. Fight it.
Eclipse phase is a Transhumanist RPG published by Posthuman Studios. It was released in 2009 and all Eclipse Phase products (including printed rulebooks/sourcebooks and PDFs) by Posthuman Studios are licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 License. This means it's actually legal to go out and download it and share it with whoever you want. The game is set around 10 years after the singularity (called the Fall in the game) renders earth a nano-technological wasteland and trans-humanity lives scattered around the solar system. Characters typically work for a shadowy organization called 'Firewall', who are attempting to ensure the survival of the solar system.
The game was originally published by Catalyst Game Labs but is now published by Posthuman Studios.
In the not too distant future...
There was a massive war between first world nations and corporations, then the singularity happened, and a bunch of AIs went crazy due to an alien virus of some kind, Earth had to be evacuated. Now everybody lives elsewhere- on the half terraformed surface of Mars, on the moons of Jupiter and Saturn, floating above the clouds of Venus, space stations and hollowed out asteroids across the solar system. Nanotech is readily available, people can upload their minds to computers, and humans uplifted a couple of species (chimps and octopuses).
There are several Wormholes left behind by the AIs that link to various other solar systems- these are called the Pandora gates. Also, there are some aliens calling themselves 'The Factors' who claim to represent the rest of galactic civilization, but they are very mysterious.
Also there are space-whales living in the sun, and all kinds of weird ass fucking to be had.
One of the more unique things about Eclipise Phase is the differentiation between a character's Ego (mind) and Morph (body). Given the ability to upload a character's brain to a digital repository, characters can make back-ups of their personality and if one body dies, simply swap into a new one. This allows combat to be highly lethal without having to introduce new characters constantly, similar to the 6-pack system of Paranoia.
Morphs are also more varied than many standard RPGs, ranging from unaltered humans to robotic "shells" to swarms of nanotech to genetically engineered octopi.
 Mass Effect-Eclipse Phase
/tg/, in its infinte wisdom, decided to combine the setting of Eclipse phase with the Galaxy of Mass Effect. The result was some very good threads and some high quality writefaggotry.
 External links
Eclipse Phase Homepage
Creative Commons Release Information